Post Thrombotic Syndrome

Post Thrombotic Syndrome (PTS)/ Post Phlebitic Syndrome (PPS)

Post Thrombotic Syndrome (PTS)/ Post Phlebitic Syndrome (PPS) is defined as a syndrome of chronic venous insufficiency (CVI, a medical condition where the veins cannot pump enough oxygen-depleted blood back to the heart). PTS/PPS is caused by damage to the vein walls and valves following a DVT or thrombosis. As a result of incompetent valves and/or persistent venous obstruction from the thrombus, pressure increases in the veins and capillaries causing pain, swelling and redness of the lower leg.

Post Thrombotic Syndrome/ Post Phlebitic Syndrome Prevalence

Post Thrombotic Syndrome (PTS)/ Post Phlebitic Syndrome (PPS) is the most frequent complication of DVT. Statistics reveal that up to 60% of patients who have suffered from Deep Vein Thrombosis will develop PTS. The prevalence of venous ulceration (a shallow wound that develops on the lower leg due to the increase in pressure resulting from the damaged leg veins failing to return blood back to the heart) is at least 300 per 100,000 or 25% of people develop a venous wound following a DVT.

Venowave for PTS

Risk Factors for Developing Post Thrombotic Syndrome/ Post Phlebitic Syndrome

  • Age > 65
  • Proximal DVT (DVT above the knee)
  • Recurrent ipsilateral DVT (A second DVT in same leg as the first DVT)
  • Persistent DVT symptoms 1 month after DVT diagnosis
  • Obesity
  • Poor quality anti-coagulant control during the first 3 months of treatment

Symptoms of Post Thrombotic Syndrome/Post Phlebitic Syndrome

  • Chronic Swelling
  • Chronic Pain (aching or cramping)
  • Chronic Heaviness
  • Itching or tingling
  • Skin ulcers
  • Varicose Veins
  • Brownish or reddish skin discoloration

Symptoms may grow worse as the day continues or following long periods of standing but decrease in severity after leg elevation.

The Villalta Scale

Doctors may use the Villalta Scale to diagnosis PTS.
  • Includes subjective and objective components
  • Diagnosis may get delayed for 3-6 months following a DVT diagnosis because signs and symptoms are similar to those of DVT

Sometimes it is possible to be diagnosed with PTS without being previously diagnosed with a DVT as sometimes DVTs are asymptomatic, where the patient does not show any symptoms.

Chronic venous insufficiency
A pictorial representation of a healthy vein valve vs. an unlhealthy valve

Chronic Venous Insufficiency (CVI)

Chronic Venous Insufficiency (CVI) occurs when the veins cannot pump enough blood back to the heart. CVI is sometimes referred to as an "impaired musculovenous pump" due to damaged or incompetent valves. Valves in the vein may become damaged after the development of deep vein thrombosis (DVT).

Traditional Treatment for Post Thrombotic Syndrome/Post Phlebitic Syndrome & Chronic Venous Insufficiency (CVI)

  • Compression stockings and leg elevation are considered to be the traditional gold standard in PTS treatment- until today.
  • Sometimes herbal remedies may be used as well.
  • The focus is to reduce venous stasis (stagnant blood in the lower leg).
  • Current therapies are limited and often ineffective.
  • Compression stockings are often not fitted correctly and patient compliance is poor.
Venowave Leg Application

How the Venowave Can Help

Post Thrombotic Syndrome patients have traditionally been an underserved population- until today.

The Venowave is a medical device that has been statistically proven to alleviate the symptoms associated with Post Thrombotic Syndrome (PTS) / Post Phlebitic Syndrome (PPS) or Chronic Venous Insufficiency (CVI), allowing patients to resume activities of daily living.

The Venowave is applied to the back of the calf and mimics the body's venous system by forcing the blood to be pumped from the affected leg. This pumping action reduces swelling, pain, heaviness & other symptoms of PTS/PPS. The Venowave is unique because it is lightweight (270g, about half a pound), discreet (can be easily worn under pants or skirts), and allows patients to remain completely mobile. There are no wires, tubes or sleeves and the device can be worn all day long.

The Venowave is Useful For:

  • Compression
  • Post Thrombotic Syndrome Prevention
  • Management of the symptoms of Post Thrombotic Syndrome (PTS)
  • Treatment of leg swelling due to vascular insufficiency
  • Treatment of varicose veins
  • Treatment of Chronic Venous Insufficiency (CVI)