Clinical Studies

Deep Vein Thrombosis

obieraj-Teague M, Hirsh J, Yip G, Gastaldo F, Stokes T, Sloane D, O’Donnell MJ, Eikelboom JW. (2011). "ORIGINAL ARTICLE Randomized controlled trial of a new portable calf compression device (Venowave) for prevention of venous thrombosis in high-risk neurosurgical patients". Journal of Thrombosis and Haemostasis 10 (229–35): 7. DOI:10.1111/j.1538-7836.2011.04598.x.

M. Griffin A.N. Nicolaides D. Bond G. Geroulakos E. Kalodiki "The Efficacy of a New Stimulation Technology to Increase Venous Flow and Prevent Venous Stasis"European Journal of Vascular and Endovascular Surgery (2010) 40, 766-771

Alexander G. G. Turpie, FRCP; Jack Hirsh, MD; Michael Gent, MS; Denise Julian, MS; Judith Johnson, RN "Prevention of Deep Vein Thrombosis in Potential Neurosurgical Patients"Archives of Internal Medicine March 1989;149(3):679-681. (Abstract)

Post Thrombotic Syndrome

O'Donnell MJ, McRae S, Kahn SR, Julian JA, Kearon C, Mackinnon B, Magier D, Strulovich C, Lyons T, Robinson S, Hirsh J, Ginsberg JS. (March 2008). "Evaluation of a venous-return assist device to treat severe post-thrombotic syndrome (VENOPTS). A randomized controlled trial". Thromb Haemost. 3 (623-9). PMID 18327413.

O'Donnell MJ, McRae S, Kahn SR, Julian JA, Kearon C, Mackinnon B, Magier D, Strulovich C, Lyons T, Robinson S, Hirsh J, Ginsberg JS (2002). "Effects of a novel venous return assist device (Venowave) on lowe limb venous flow in patients with post-thrombotic syndrom". Journal of the American Society of Hematology. Blood.


Steven J. Kavros, DPM, Konstantinos T. Delis, MD, MS, PhD, FRCSI, EBSQvasc, Norman S. Turner, MD, Anthony E. Voll, RN, Davis A. Liedl, RN, Peter Gloviczki, MD, Thom W. Rooke, MD "Improving limb salvage in critical ischemia with intermittent pneumatic compression: A controlled study with 18 month follow up"Journal of Vascular Surgery Volume 47, Issue 3 , Pages 543-549, March 2008

Venous ulcers are wounds that are thought to occur due to improper functioning of venous valves, usually of the legs. They are the major cause of chronic wounds, occurring in 70% to 90% of chronic wound cases. Venous Ulcers can be very painful and a costly problem. Current treatments are labour intense and painful.

Saringer Life Science Technologies Inc. has noted in many anecdotal case study reviews that 100% percent of patients with long standing chronic foot ulcers that would not respond to any existing treatment, the Venowave contributed to rapidly healing the wounds. Such a result has prompted Dr. Jack Hirsh, Chief Science Officer and professor emeritus in medicine at McMaster Univerisity, to plan and lead a full randomized clinical trial to commence in 2012.

Athletic Enhancement

Avigdor Zelikovski MD, Clive L. Kaye MSc, Gershon Fink, Shimon A Spitzer MD and Yair Shapirot MD "The effects of the modified intermittent sequential pneumatic device(MISPD) on exercise performance following an exhaustive exercise bout."British Journal of Sports Medicine 1993; 27(4) Br J Sports Med 1993;27:255-259 DOI: 10.1136/bjsm.27.4.255